Scientific References

Thank you for consulting our scientific reference section. Below is just a small sample of the supportive studies regarding your particular area of interest. Studies may be directly or indirectly related to this area of health care. We pride ourselves upon “thinking outside of the box” such that we base much of our wellness approaches upon a scientific evidence base.  It is important for you to realize that the references below are not provided to necessarily support the particular approach described within this section of our website.  If you would like further evidence or support or simply have questions please feel free to contact Us.

http://www.ncbi.nlm.nih.gov/pubmed/20671743 -Shows that the Bioimpedance analysis (BIA) of extracellular/intracellular cell mass is a significant indirect predictor of mortality in peritoneal dialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/14531774 – This study shows that Bioimpedance analysis (BIA) indexes reflect the nutritional status in peritoneal dialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/12028177 – Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. Bioimpedance analysis measurements estimated the amount of skeletal muscle mass and helped in the observation and determination of increased morbidity and mortality in older patients.

http://www.ncbi.nlm.nih.gov/pubmed/21184919 – Bioimpedance analysis in conjunction with blood work and physical performance measurements helps in the determination of functional health in hemodialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/20863969 – BIA is a good assessment of nutritional status in patients with Chronic Obstructive Pulmonary Disease (COPD).

http://www.ncbi.nlm.nih.gov/pubmed/16701923 – Supplemental creatinine improved bioimpedane parameters that may be predictors of nutritional status in colorectal cancer patients.

http://www.ncbi.nlm.nih.gov/pubmed/20467382 -Bioimpedance analysis may be used along side other measurements as an assessment of nutritional status in children with Chronic Kidney Disease.

http://www.ncbi.nlm.nih.gov/pubmed/20097150 – The use of bioimpedance in the detection/screening of tongue cancer.

http://www.ncbi.nlm.nih.gov/pubmed/14618476 -Bioimpedance analysis is a useful procedure for the study of nutritional status, water distribution and its measurement of fat-free mass in children.

http://www.ncbi.nlm.nih.gov/pubmed/17452840 – This study showed the use of bioimpedance analysis to evaluate lymphedema.

http://www.ncbi.nlm.nih.gov/pubmed/2197849 – BIA is a useful clinical method for measuring change in body composition.

Longevity Plan References

http://www.ncbi.nlm.nih.gov/pubmed/20671743 -Shows that the Bioimpedance analysis (BIA) of extracellular/intracellular cell mass is a significant indirect predictor of mortality in peritoneal dialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/14531774 – This study shows that Bioimpedance analysis (BIA) indexes reflect the nutritional status in peritoneal dialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/12028177 – Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. Bioimpedance analysis measurements estimated the amount of skeletal muscle mass and helped in the observation and determination of increased morbidity and mortality in older patients.

http://www.ncbi.nlm.nih.gov/pubmed/21184919 – Bioimpedance analysis in conjunction with blood work and physical performance measurements helps in the determination of functional health in hemodialysis patients.

http://www.ncbi.nlm.nih.gov/pubmed/20863969 – BIA is a good assessment of nutritional status in patients with Chronic Obstructive Pulmonary Disease (COPD).

http://www.ncbi.nlm.nih.gov/pubmed/16701923 – Supplemental creatinine improved bioimpedane parameters that may be predictors of nutritional status in colorectal cancer patients.

http://www.ncbi.nlm.nih.gov/pubmed/20467382 -Bioimpedance analysis may be used along side other measurements as an assessment of nutritional status in children with Chronic Kidney Disease.

http://www.ncbi.nlm.nih.gov/pubmed/20097150 – The use of bioimpedance in the detection/screening of tongue cancer.

http://www.ncbi.nlm.nih.gov/pubmed/14618476 -Bioimpedance analysis is a useful procedure for the study of nutritional status, water distribution and its measurement of fat-free mass in children.

http://www.ncbi.nlm.nih.gov/pubmed/17452840 – This study showed the use of bioimpedance analysis to evaluate lymphedema.

http://www.ncbi.nlm.nih.gov/pubmed/2197849 – BIA is a useful clinical method for measuring change in body composition.

Bio-Identical Hormone References

http://www.ncbi.nlm.nih.gov/pubmed/8865138 – t is concluded that hormone replacement therapy, with estrogens alone or estrogens combined with progestins, may have important effects on the risk of cancer, particularly in the breast and endometrium. Therefore, when making a risk-benefit assessment of long-term HRT, possible risk relationships should be considered.

http://www.ncbi.nlm.nih.gov/pubmed/21464264 – Bioidentical hormones that are approved by the FDA may be preferred over standard hormone replacement because of their physiologic benefits and safetyprofile.

http://www.ncbi.nlm.nih.gov/pubmed/17217322 – Bioidentical hormone preparations have demonstrated effectiveness in addressing menopausal symptoms. The author advocates for continued research on bioidentical hormones and concludes there is currently sufficient evidence to support their preferred use over that of their synthetic cousins.
http://www.ncbi.nlm.nih.gov/pubmed/12201829 – treatment with GH replacement therapy, improvements in QoL are observed and maintained long-term over several years.

http://www.ncbi.nlm.nih.gov/pubmed/19020387 – Measurements of quality of life in patients with growth hormone deficiency.

http://www.ncbi.nlm.nih.gov/pubmed/21969523 – The presence of MetS (metabolic syndrome) in GHD may therefore contribute to the increased risk of cardiovascular morbidity and mortality found in these patients.

http://www.ncbi.nlm.nih.gov/pubmed/18537700 – Growth hormone and insulin-like growth factor-I as an endocrine axis in Alzheimer’s disease.

http://www.ncbi.nlm.nih.gov/pubmed/21865409 – Growth hormone therapy in adults with confirmed GH deficiency reduces weight and body fat, increases lean body mass and increases edema and joint stiffness. Most trials demonstrated improvement in quality of life measures.

http://www.ncbi.nlm.nih.gov/pubmed/15320746 – In terms of the mechanisms for the age-related impairment in bone formation, a deficiency in growth hormone (GH)/insulin-like growth factor (IGF) system that occurs with age has been proposed to play a major role.

http://www.ncbi.nlm.nih.gov/pubmed/20930497 – GH/IGF-I axis is involved in the regulation of brain growth, development, and metabolism. Dysfunctions in GH/IGF-I axis in most of ND are therefore reviewed.

http://www.ncbi.nlm.nih.gov/pubmed/22023735 – The pilot study showed that combined treatment with an oral testosterone and a supplement drink was well tolerated and safe, and reduced the number of people hospitalised and duration of hospital admissions in undernourished, community dwelling older people.

http://www.ncbi.nlm.nih.gov/pubmed/21797916 – Testosterone appears to maintain insulin sensitivity in normal men.

http://www.ncbi.nlm.nih.gov/pubmed/12425705 –  In this study, GH with or without sex steroids in healthy, aged women and men increased LBM and decreased fat mass.

http://www.ncbi.nlm.nih.gov/pubmed/19602554 – GH administration to healthy older individuals for 6 months increased insulin resistance with moderately beneficial effects on lipids.

Arterial Elasticity References

ncbi.nlm.nih.gov/pubmed/21127698 – This study demonstrates that improvement in arterial stiffness identifies patients who have a more favorable prognosis.

ncbi.nlm.nih.gov/pubmed/17877923 – Promising study results show that measurement of arterial stiffness could become an important part of the routine assessment of patients in daily practice.

ncbi.nlm.nih.gov/pubmed/10472072 – This new concept should lead physicians to evaluate arterial stiffness for the prognosis and treatment of cardiovascular patients.

ncbi.nlm.nih.gov/pubmed/21179973 – Cardiovascular events from arterial stiffness ncbi.nlm.nih.gov/pubmed/21177171 – Sleep apnea increases cardiovascular problems

ncbi.nlm.nih.gov/pubmed/21166628 – Emphesema, cardiovascular events and artery stiffness (calcification).

ncbi.nlm.nih.gov/pubmed/21127697 – These results suggest long-term ingestion of SSE in humans could help to improve arterial stiffness.

ncbi.nlm.nih.gov/pubmed/21122858 – The present study suggests that elevation of ApoB or non-HDL cholesterol is associated with increased arterial stiffness in young adults.

ncbi.nlm.nih.gov/pubmed/21076576 – These results can imply the deleterious effect of acute hyperglycemic excursion on arterial stiffness in subjects with glucose intolerance.

ncbi.nlm.nih.gov/pubmed/21070721 – Measurement of arterial stiffness is a sensitive technique that can detect vascular damage in children with cardiovascular risk factors earlier than intima-media thickness measurement.

ncbi.nlm.nih.gov/pubmed/21103036 – Patients who have prominently increased arterial stiffness can be recommended to undergo colonoscopic examinations and at the same time we also recommend counseling about the risk for atherosclerosis in those who have colorectal adenomas.

ncbi.nlm.nih.gov/pubmed/16782104 – CRP could be a useful marker of arterial stiffness in treated hypertension patients and a possible target for arterial inflammation in hypertension.

ncbi.nlm.nih.gov/pubmed/20954972 – Renal artery stiffness is associated with arterial resistance (stiffness).

ncbi.nlm.nih.gov/pubmed/20660051 – In young obese women with PCOS, (central) obesity, rather than PCOS itself, is associated with increased arterial stiffness. ncbi.nlm.nih.gov/pubmed/20610595 – Obesity is associated with increased arterial stiffness.

Autonomic Nervous References

http://www.ncbi.nlm.nih.gov/pubmed/22006687 –  Exercise training improves autonomic profiles in patients with Charcot-Marie-Tooth disease.

http://www.ncbi.nlm.nih.gov/pubmed/22002186 – The relationship between cardiac autonomic function and clinical and angiographic characteristics in patients with coronary artery disease.

http://www.ncbi.nlm.nih.gov/pubmed/21996103 – Heart Rate Variability in Assessment of Autonomic Dysfunction in Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome.

http://www.ncbi.nlm.nih.gov/pubmed/15923026 – Analysis of heart rate variability in female patients with overactive bladder.

http://www.ncbi.nlm.nih.gov/pubmed/15649231 – Heart rate variability in patients with essential hyperhidrosis: dynamic influence of sympathetic and parasympathetic maneuvers.

http://www.ncbi.nlm.nih.gov/pubmed/14639860 – [Changes in autonomic control of heart rate after ischemic cerebral stroke].

http://www.ncbi.nlm.nih.gov/pubmed/22014539 – Exploring autonomic nervous system dysfunction in patients with cancer cachexia: A pilot study.

http://www.ncbi.nlm.nih.gov/pubmed/21388744 – Sympathetic and parasympathetic activity in cancer-related fatigue: more evidence for a physiological substrate in cancersurvivors.

http://www.ncbi.nlm.nih.gov/pubmed/21123449 – Treatment of obstructive sleep apnea improves cardiometabolic function in young obese women with polycystic ovary syndrome.

http://www.ncbi.nlm.nih.gov/pubmed/20676323 – Heart rate variability and length of survival in hospice cancer patients.

http://www.ncbi.nlm.nih.gov/pubmed/20413055 – Association between cardiovascular autonomic functions and time to death in patients with terminal hepatocellular carcinoma.

http://www.ncbi.nlm.nih.gov/pubmed/20224872 – Heart rate variability during and after peripheral blood stem cell leukapheresis in autologous transplant patients and allogeneic transplant donors.

http://www.ncbi.nlm.nih.gov/pubmed/21985749 – Inspiratory muscle training reduces blood pressure and sympathetic activity in hypertensive patients: A randomized controlled trial.

http://www.ncbi.nlm.nih.gov/pubmed/21748930 – Impaired heart rate variability as a marker of cardiovascular autonomic dysfunction in multiple sclerosis.

http://www.ncbi.nlm.nih.gov/pubmed/21306747 – Abnormal left ventricular torsion and cardiac autonomic dysfunction in subjects with type 1 diabetes mellitus.

http://www.ncbi.nlm.nih.gov/pubmed/21089445 – [Prospects for the assessment of cardiac rhythm variability in patients with rheumatoid arthritis and systemic lupus erythematosus].

Body Composition References

Reference – Shows that the Bioimpedance analysis (BIA) of extracellular/intracellular cell mass is a significant indirect predictor of mortality in peritoneal dialysis patients.

Reference – This study shows that Bioimpedance analysis (BIA) indexes reflect the nutritional status in peritoneal dialysis patients.

Reference – Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. Bioimpedance analysis measurements estimated the amount of skeletal muscle mass and helped in the observation and determination of increased morbidity and mortality in older patients.

Reference – Bioimpedance analysis in conjunction with blood work and physical performance measurements helps in the determination of functional health in hemodialysis patients.

Reference – BIA is a good assessment of nutritional status in patients with Chronic Obstructive Pulmonary Disease (COPD).

Reference – Supplemental creatinine improved bioimpedane parameters that may be predictors of nutritional status in colorectal cancer patients.

Reference -Bioimpedance analysis may be used along side other measurements as an assessment of nutritional status in children with Chronic Kidney Disease.

Reference – The use of bioimpedance in the detection/screening of tongue cancer.
Reference -Bioimpedance analysis is a useful procedure for the study of nutritional status, water distribution and its measurement of fat-free mass in children.

Reference – This study showed the use of bioimpedance analysis to evaluate lymphedema.

Reference – BIA is a useful clinical method for measuring change in body composition.

Reference – Bioelectrical impedance phase angle as a prognostic indicator in breast cancer

Cardio-Beam Pulse Wave References